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Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients
Yang Sun,Chenze Li,Lina Zhang,Dong Hu,Xudong Zhang,Ting Yu,Min Tao,Dao Wen Wang,Xiaoqing Shen
Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 53-61 doi: 10.1007/s11684-017-0502-2
Low adherence to secondary prevention medications (ATM) of patients after acute coronary syndromeA total of 2126 patients were classified under low adherence (proportion of days covered (PDC)<50%) and high adherence (PDC>50%) groups based on their performance after discharge.In conclusion, PCI-treated patients are more prone to remaining adherent to medications than CABG-treatedHigh adherence to P2Y12 antagonists was associated with lower risk of MACE.
Keywords: acute coronary syndromes adherence to secondary prevention medications clinical outcome
Health: a dream from reality to the future
Chunsong Hu,Qinghua Wu
Frontiers of Medicine 2016, Volume 10, Issue 2, Pages 233-235 doi: 10.1007/s11684-016-0444-0
Keywords: health promotion primary and secondary prevention policy prevention infectious disease non-communicable
Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 4, doi: 10.1007/s11783-020-1368-0
• SMX was mainly degraded by hydrolysis, isoxazole oxidation and double-bond addition.
Keywords: Sulfamethoxazole Ozonation Natural organic matters Secondary effluent Degradation mechanism
Physical and chemical processes of wintertime secondary nitrate aerosol formation
Qi YING
Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 3, Pages 348-361 doi: 10.1007/s11783-011-0343-1
Keywords: secondary nitrate aerosol N2O5 heterogeneous reaction process analysis
Two-echelon Emergency Response Problem and Simulation Considering Secondary Disasters
Han-peng Zhang,Yi Liao,Hui-xia Luo
Frontiers of Engineering Management 2014, Volume 1, Issue 3, Pages 318-321 doi: 10.15302/J-FEM-2014042
Keywords: simulation secondary disasters two-echelon vehicle routing model
Formation of secondary inorganic aerosol in a frigid urban atmosphere
Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 2, doi: 10.1007/s11783-021-1452-0
•Harbin showed relatively high threshold RH (80%) for apparent increase of SOR.
Keywords: Haze Sulfate Nitrate Heterogeneous chemistry Biomass burning Northeast China
Haiqian LI, Yonglong LU, Li LI
Frontiers of Environmental Science & Engineering 2013, Volume 7, Issue 4, Pages 589-597 doi: 10.1007/s11783-013-0495-2
Keywords:
polychlorinated dibenzo-
Liangyun Zhou,Guang Yang,Haifeng Sun,Jinfu Tang,Jian Yang,Yizhan Wang,Thomas Avery Garran,Lanping Guo
Frontiers of Medicine 2017, Volume 11, Issue 1, Pages 137-146 doi: 10.1007/s11684-016-0486-3
This study aims to elucidate the underlying molecular mechanisms of artemisinin accumulation induced by cadmium (Cd). The effects of different Cd concentrations (0, 20, 60, and 120 μmol/L) on the biosynthesis of Artemisia annua L. were examined. Intermediate and end products were quantified by HPLC-ESI-MS/MS analysis. The expression of key biosynthesis enzymes was also determined by qRT-PCR. The results showed that the application of treatment with 60 and 120 μmol/L Cd for 3 days significantly improved the biosynthesis of artemisinic acid, arteannuin B, and artemisinin. The concentrations of artemisinic acid, arteannuin B, and artemisinin in the 120 μmol/L Cd-treated group were 2.26, 102.08, and 33.63 times higher than those in the control group, respectively. The concentrations of arteannuin B and artemisinin in 60 μmol/L Cd-treated leaves were 61.10 and 26.40 times higher than those in the control group, respectively. The relative expression levels of HMGR, FPS, ADS, CYP71AV1, DBR2, ALDH1, and DXR were up-regulated in the 120 μmol/L Cd-treated group because of increased contents of artemisinic metabolites after 3 days of treatment. Hence, appropriate doses of Cd can increase the concentrations of artemisinic metabolites at a certain time point by up-regulating the relative expression levels of key enzyme genes involved in artemisinin biosynthesis.
Keywords: Cd secondary metabolites gene expressions Artemisia annua L.
Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China
Rui Yu,Rong Fan,Jinlin Hou
Frontiers of Medicine 2014, Volume 8, Issue 2, Pages 135-144 doi: 10.1007/s11684-014-0331-5
Chronic hepatitis B is a major health problem in China. The universal vaccination program since 1992 has changed the epidemiology of hepatitis B virus infection in China from highly to moderately endemic. The most prevalent hepatitis B virus strains in China are genotypes B and C, whereas those in western provinces are genotypes D and C/D hybrid. Chronic hepatitis B poses a heavy burden to the society in China. Different treatment strategies have been explored to improve patient outcomes in a cost-effective manner. However, antiviral drugs with a low genetic barrier to resistance are still extensively used because of the generally low income and limited resources in China. Individualized antiviral therapy is closely associated with translational medicine, which utilizes information from studies on genomics, immune biomarkers, and fibrosis. The results of these studies are crucial in further improving treatment outcomes.
Keywords: chronic hepatitis B epidemiology prevention treatment
Simple model of sludge thickening process in secondary settlers
Yuankai ZHANG,Hongchen WANG,Lu QI,Guohua LIU,Zhijiang HE,Songzhu JIANG
Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 2, Pages 319-326 doi: 10.1007/s11783-014-0758-6
Keywords: wastewater treatment plants secondary settler sludge thickening sludge settling hindered zone
On the location of the secondary instantaneous poles in two-degree-of-freedom spherical mechanisms
Soheil ZARKANDI
Frontiers of Mechanical Engineering 2014, Volume 9, Issue 1, Pages 34-40 doi: 10.1007/s11465-014-0290-1
Keywords: spherical mechanisms instantaneous poles great circle angular velocity
Xiliang ZHANG, Zhiying CUI, Jianhan ZHANG, Fengwu BAI, Zhifeng WANG
Frontiers in Energy 2019, Volume 13, Issue 3, Pages 590-596 doi: 10.1007/s11708-018-0602-y
Keywords: secondary parabolic trough solar concentrator ray tracing method linear focus concentration ratio optical
Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development
Long-de Wang
Frontiers of Engineering Management 2015, Volume 2, Issue 1, Pages 2-12 doi: 10.15302/J-FEM-2015002
Keywords: chronic disease prevention and control strategy and system construction
Relationship between the number of tapping-induced secondary laticifer lines and rubber yield among
Yueyi CHEN,Xinsheng GAO,Xiaofei ZHANG,Weimin TIAN
Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4, Pages 363-367 doi: 10.15302/J-FASE-2016122
Keywords: Hevea brasiliensis rubber yield breeding early evaluation tapping secondary laticifer differentiation
A method for quantifying bias in modeled concentrations and source impacts for secondary particulate
Cesunica E. Ivey, Heather A. Holmes, Yongtao Hu, James A. Mulholland, Armistead G. Russell
Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 5, doi: 10.1007/s11783-016-0866-6
Keywords: Particulate matter Source apportionment Secondary particulate matter Chemical transport modeling Receptor
Title Author Date Type Operation
Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients
Yang Sun,Chenze Li,Lina Zhang,Dong Hu,Xudong Zhang,Ting Yu,Min Tao,Dao Wen Wang,Xiaoqing Shen
Journal Article
Mechanisms for simultaneous ozonation of sulfamethoxazole and natural organic matters in secondary effluent
Journal Article
Physical and chemical processes of wintertime secondary nitrate aerosol formation
Qi YING
Journal Article
Two-echelon Emergency Response Problem and Simulation Considering Secondary Disasters
Han-peng Zhang,Yi Liao,Hui-xia Luo
Journal Article
PCDD/Fs emission, risk characterization, and reduction in China’s secondary copper production industry
Haiqian LI, Yonglong LU, Li LI
Journal Article
Effects of different doses of cadmium on secondary metabolites and gene expression in Artemisia annua
Liangyun Zhou,Guang Yang,Haifeng Sun,Jinfu Tang,Jian Yang,Yizhan Wang,Thomas Avery Garran,Lanping Guo
Journal Article
Chronic hepatitis B virus infection: epidemiology, prevention, and treatment in China
Rui Yu,Rong Fan,Jinlin Hou
Journal Article
Simple model of sludge thickening process in secondary settlers
Yuankai ZHANG,Hongchen WANG,Lu QI,Guohua LIU,Zhijiang HE,Songzhu JIANG
Journal Article
On the location of the secondary instantaneous poles in two-degree-of-freedom spherical mechanisms
Soheil ZARKANDI
Journal Article
Optical performance analysis of an innovative linear focus secondary trough solar concentrating system
Xiliang ZHANG, Zhiying CUI, Jianhan ZHANG, Fengwu BAI, Zhifeng WANG
Journal Article
Exploration of Strategies for Chronic Disease Prevention and Control and Relevant System Development
Long-de Wang
Journal Article
Relationship between the number of tapping-induced secondary laticifer lines and rubber yield among
Yueyi CHEN,Xinsheng GAO,Xiaofei ZHANG,Weimin TIAN
Journal Article